Andreas von Deimling Selected Research

Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))

5/2022	Dysfunctional dendritic cells limit antigen-specific T cell response in glioma.
1/2022	Temozolomide and Radiotherapy versus Radiotherapy Alone in Patients with Glioblastoma, IDH-wildtype: Post Hoc Analysis of the EORTC Randomized Phase III CATNON Trial.
1/2021	Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas.
1/2021	Telomerase reverse transcriptase promoter mutation- and O6-methylguanine DNA methyltransferase promoter methylation-mediated sensitivity to temozolomide in isocitrate dehydrogenase-wild-type glioblastoma: is there a link?
10/2020	An activating germline IDH1 variant associated with a tumor entity characterized by unilateral and bilateral chondrosarcoma of the mastoid.
10/2020	Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma.
1/2020	FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.
1/2020	Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
1/2020	T2/FLAIR-mismatch sign for noninvasive detection of IDH-mutant 1p/19q non-codeleted gliomas: validity and pathophysiology.
1/2020	Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma.

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Andreas von Deimling Research Topics

Disease

226	Neoplasms (Cancer) 12/2022 - 07/2002
103	Glioma (Gliomas) 12/2022 - 10/2004
90	Glioblastoma (Glioblastoma Multiforme) 05/2022 - 08/2002
39	Astrocytoma (Pilocytic Astrocytoma) 12/2022 - 08/2002
27	Brain Neoplasms (Brain Tumor) 01/2022 - 05/2006
20	Meningioma (Meningiomas) 12/2022 - 09/2006
17	Oligodendroglioma 12/2022 - 10/2004
17	Medulloblastoma 01/2022 - 03/2010
16	Melanoma (Melanoma, Malignant) 01/2022 - 02/2012
11	Neoplasm Metastasis (Metastasis) 11/2021 - 08/2004
11	Sarcoma (Soft Tissue Sarcoma) 01/2021 - 06/2011
11	Neurofibrosarcoma (MPNST) 01/2016 - 02/2004
9	Carcinogenesis 01/2020 - 04/2004
8	Disease Progression 11/2021 - 10/2005
7	Neuroblastoma 03/2020 - 05/2007
6	Carcinoma (Carcinomatosis) 11/2021 - 03/2005
5	Necrosis 01/2020 - 04/2009
5	Ependymoma 01/2017 - 03/2009
4	Solitary Fibrous Tumors 01/2022 - 05/2013
4	Primitive Neuroectodermal Tumors (PNET) 01/2021 - 01/2016
4	Neurilemmoma (Schwannoma) 01/2020 - 04/2014
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/2017 - 08/2010
4	Lung Neoplasms (Lung Cancer) 12/2014 - 02/2009
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2022 - 03/2009
3	Lymphoma (Lymphomas) 01/2021 - 08/2004
3	Hemangiosarcoma (Angiosarcoma) 01/2021 - 04/2014
3	Genomic Instability 12/2019 - 01/2016
3	Chondrosarcoma 08/2018 - 04/2014
3	Inflammation (Inflammations) 04/2016 - 06/2007
3	Colorectal Neoplasms (Colorectal Cancer) 12/2014 - 02/2012
3	Breast Neoplasms (Breast Cancer) 12/2014 - 11/2003
3	Adenocarcinoma 11/2014 - 10/2013
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2014 - 06/2011

Drug/Important Bio-Agent (IBA)

72	Proteins (Proteins, Gene)FDA Link 12/2022 - 08/2002
55	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 05/2022 - 12/2008
44	DNA (Deoxyribonucleic Acid)IBA 12/2022 - 08/2002
34	Biomarkers (Surrogate Marker)IBA 12/2022 - 12/2007
30	Biological ProductsIBA 01/2022 - 08/2004
23	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 10/2005
20	ParaffinIBA 12/2022 - 09/2009
19	RNA (Ribonucleic Acid)IBA 10/2022 - 02/2004
17	Messenger RNA (mRNA)IBA 01/2020 - 03/2005
14	Formaldehyde (Formol)FDA Link 12/2022 - 11/2009
14	Pharmaceutical PreparationsIBA 12/2021 - 05/2007
13	EnzymesIBA 01/2021 - 09/2006
10	Histones (Histone)IBA 01/2019 - 01/2010
9	AntigensIBA 05/2022 - 02/2015
9	alpha-hydroxyglutarateIBA 10/2020 - 01/2012
8	MethyltransferasesIBA 01/2021 - 01/2011
8	Codon (Codons)IBA 01/2021 - 12/2008
8	LigandsIBA 01/2013 - 11/2003
7	Peptides (Polypeptides)IBA 01/2022 - 02/2006
7	ErbB Receptors (EGF Receptor)IBA 01/2021 - 12/2008
7	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 10/2011
7	MicroRNAs (MicroRNA)IBA 01/2020 - 04/2009
6	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021 - 12/2013
6	Phosphotransferases (Kinase)IBA 01/2020 - 01/2012
6	Small Interfering RNA (siRNA)IBA 04/2019 - 01/2008
6	Alkylating AgentsIBA 02/2016 - 01/2012
6	Monoclonal AntibodiesIBA 10/2015 - 01/2010
6	O(6)-Methylguanine-DNA MethyltransferaseIBA 07/2014 - 12/2009
5	NucleotidesIBA 11/2021 - 01/2016
5	Amino Acids FDA Link 01/2021 - 08/2002
5	VaccinesIBA 01/2021 - 08/2014
5	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2021 - 10/2011
5	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2020 - 12/2008
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 11/2008
5	Neurofibromin 1 (Neurofibromin)IBA 01/2016 - 07/2004
4	Neoplasm Antigens (Tumor Antigens)IBA 05/2022 - 11/2018
4	ProteomeIBA 01/2022 - 11/2018
4	ChromatinIBA 12/2019 - 01/2012
4	TensinsIBA 01/2018 - 09/2005
4	Mitogen-Activated Protein KinasesIBA 01/2018 - 03/2013
4	EpitopesIBA 01/2018 - 02/2015
4	Matrix Metalloproteinases (MMPs)IBA 01/2018 - 09/2006
4	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2018 - 02/2004
4	isocitric acid (isocitrate)IBA 09/2017 - 08/2010
4	Transcription Factors (Transcription Factor)IBA 01/2015 - 09/2006
4	Histone Deacetylase InhibitorsIBA 05/2014 - 01/2009
4	Mutant Proteins (Protein, Mutant)IBA 03/2013 - 02/2012
3	KynurenineIBA 01/2021 - 10/2011
3	Cyclin-Dependent Kinases (cdk Proteins)IBA 12/2020 - 12/2009
3	Bevacizumab (Avastin)FDA Link 10/2020 - 10/2015
3	SurvivinIBA 03/2020 - 11/2008
3	Interleukin-6 (Interleukin 6)IBA 01/2019 - 08/2010
3	Membrane Proteins (Integral Membrane Proteins)IBA 01/2019 - 09/2009
3	Fas Ligand Protein (Fas Ligand)IBA 01/2018 - 03/2008
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 09/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018 - 07/2010
3	Lomustine (CCNU)FDA Link 11/2017 - 12/2009
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 10/2015 - 11/2003
3	Tyrosine Kinase InhibitorsIBA 11/2014 - 03/2006
3	AntibodiesIBA 08/2014 - 02/2004

Therapy/Procedure

80	Therapeutics 01/2022 - 07/2002
36	Radiotherapy 01/2022 - 01/2007
34	Drug Therapy (Chemotherapy) 01/2022 - 01/2005
9	Immunotherapy 05/2022 - 02/2015
8	Chemoradiotherapy 11/2016 - 03/2009
5	Aftercare (After-Treatment) 01/2021 - 05/2006
5	Ligation 02/2015 - 07/2010